Hanoi56-year-old man, with dull pain in the right lower quadrant for many days, accompanied by jaundice, dark urine, discolored stools, the doctor discovered cholangiocarcinoma with liver metastases.
The patient appeared unusual symptoms 4 months ago, losing weight. Doctors at Bach Mai Hospital diagnosed biliary obstruction due to a tumor in the lower part of the common bile duct, prescribed laparoscopic pancreaticoduodenectomy, biliary-enteric anastomosis, and transferred the patient to the Nuclear Medicine and Oncology Center for treatment.
On December 17, Doctor Pham Cam Phuong, Director of the Center, announced the surgical results of patients with cholangiocarcinoma, invasion of the pancreas, duodenum, and damage to the liver due to liver metastasis. After 6 cycles of intravenous infusion and chemotherapy, the patient responded well, tumor markers decreased to normal levels, and CT scans showed no tumors in the liver and abdomen. Currently, the patient continues treatment and improves his health.
Cholangiocarcinoma are malignant lesions originating from epithelial cells of the biliary tract, including ampulla of Vater cancer, gallbladder cancer, intrahepatic cholangiocarcinoma and extrahepatic cholangiocarcinoma. Cholangiocarcinoma can metastasize beyond the bile duct to other intrahepatic locations, the peritoneum, and distant extrahepatic organs.
Cholangiocarcinoma often has no obvious symptoms in the early stages, signs such as jaundice, itchy skin, vomiting, and fatigue appear when the disease is severe. Some signs include yellow skin or eyes, itchy skin, white or pale stools, dark urine, fatigue, nausea and vomiting, lower right abdominal pain, fever, night sweats, weight loss undefined reason.
It is currently difficult to detect cholangiocarcinoma early. The techniques of endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic cholangiography (PTC) and endoscopic ultrasound (EUS) help detect the disease, especially when it is necessary to determine the histological nature of the tumor. In addition, the doctor will take a biopsy to determine the histological nature of the tumor cells and provide the most accurate treatment regimen.
Doctors recommend that high-risk groups such as those over 50 years old, smoking for many years, people working in environments exposed to toxic chemicals, radioactive substances or in a family with many people with cancer, need to be examined. regular health check to prevent disease.