Using fossils and genetic techniques, experts first create three young people of the Aenocyon Dirus wolf.
Three young children belong to the wolf Aenocyon dread Has extinct. Video: Colossal Biosciences
Wolf Aenocyon dread extinct about 12,500 years ago, but now, scientists at the Biotechnology and Genetic Technology Company Colossal Biosciences have brought them back, Live Science On 7/4 reported. The group of scientists said that they successfully created three young animals of this animal, including two males Romulus, Remus and Children Khaleesi.
“Our group has taken DNA from a 13,000 -year -old tooth and a 72,000 -year -old skull to create healthy wolves,” said Ben Lamp, CEO of Colossal Biosciences.
The research team used the same process that helps Dolly sheep born in 1996. To create a perfect copy by this method, experts collect a cell from the human object and separate genetic materials, which are stored in the cell nucleus. This genetic information was then put into the eggs of an individual of the same species whose nucleus itself was removed. At this time, the eggs contain all the genetic information needed to regenerate the original clone and are put into the individual surrogate.
Wolf Aenocyon dread Determined at the end of the last ice. Therefore, in order to regenerate the genome of this animal, the team must use fossil genes and compare them with the genome of relatives who are alive like gray wolves, wild dogs, and foxes. They chose the gray wolf as an animal donating eggs, because they were the nearest relatives of the wolf Aenocyon dread.
The gene analysis helps the scientist group identify 20 main differences in 14 genes to create unique characteristics of wolves. Aenocyon dreadincluding larger size, white fur, larger teeth and characteristic howling. Next, they collect cells from the blood of the gray wolf – the less invasive method than the tissue mass like the case of Dolly sheep. After that, the application of gene crisplel editing technology, they made 20 edits with the 14 genes mentioned above so that they had the same sequence as a wolf. Aenocyon dread.
After creating wolf cells Aenocyon dreada group of experts separates their kernel and put into the egg of the gray wolf. These eggs are raised into embryos in the laboratory. The team collected 45 embryos and put into the uterus of two domestic dogs. Only one embryo in every gestational dog develops smoothly. After 65 days, Romulus and Remus wolves were born by cesarean section on October 1, 2024. After that, the whole process was repeated and the Khaleesi wolf was born on January 30, 2025.
Colossal Biosciences call it the world’s first extent of animal revival. Earlier, in 2003, scientists in Spain human beings in the extinct wild goat, Pyrenees mountain goats (Pyrenaica Pyrenaica Capra), but the young died just a few minutes after birth.
“This huge milestone is the first of many of the upcoming examples that show our extinct animal revival technology effectively,” Lamb said. Colossal Bioscience also hopes that technology helps to revive wolves Aenocyon dread Can directly help animals are threatened.