Chinese researchers have developed a nanomaterial against the SARS-CoV-2 virus

Chinese researchers have recently developed a nanomaterial that targets the spike protein of SARS-CoV-2 corona virus variants, including delta and omicron, and promotes virus elimination, Xinhua reported.Research published in the nanotechnology journal, Nature Nanotechnology, has revealed an ultrathin two-dimensional combined nanolayer made of copper, indium, phosphorus, and sulfur (CIPS) as a novel agent to combat SARS-CoV-2 virus infection.

Researchers from the Shenzhen Institute of Advanced Technologies of the Chinese Academy of Sciences, the National Center for Nanoscience and Technology, as well as the Institute of High Energy Physics and the Kunming Institute of Zoology, both within the Academy of Sciences, developed the nanomaterial and its antiviral mechanism.

According to the results of the study, this nanomaterial has an extremely high and selective binding capacity in the area of ​​binding to receptors on the spike protein of “wild type” SARS-CoV-2 and its variants, such as delta and omicron.

Testing showed that upon contact with this nanomaterial, the virus was rapidly eliminated by the host’s macrophages, suggesting that CIPS could be used to capture the virus and facilitate its elimination by the host.

Tests also showed that CIPS can inhibit virus entry and infection in cells, organoids and mice, and effectively alleviate pneumonia caused by SARS-CoV-2 infection in mice.

The study shows the potential of CIPS as a nanomedicine for the safe and effective treatment of SARS-CoV-2 infection, and as a decontamination agent and surface coating material to reduce the infectivity of the SARS-CoV-2 virus.
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